Long-term effects of remote ischaemic preconditioning in high risk patients undergoing cardiac surgery: follow-up of a randomised clinical trial

A Zarbock,D Görlich,C Schmidt,J Kellum,M Meersch,H Van Aken,S Martens

doi:10.1186/2197-425x-3-s1-a411

Abstract

Acute kidney injury (AKI) is a common complication after cardiac surgical procedures and is associated with an increased morbidity and mortality.

Highlights

Acute kidney injury (AKI) is a common complication after cardiac surgical procedures and is associated with an increased morbidity and mortality
In a multicenter randomized trial, we found that remote ischemic preconditioning (RIPC) reduced acute kidney injury (AKI) in high risk patients undergoing cardiac surgery
In this follow up of the RenalRIPC trial, we examined the effect of RIPC the composite end-point of all-cause mortality, need for renal replacement therapy, and persistent renal dysfunction at 90 days (MAKE90)

Summary

Introduction

Acute kidney injury (AKI) is a common complication after cardiac surgical procedures and is associated with an increased morbidity and mortality. Long-term effects of remote ischaemic preconditioning in high risk patients undergoing cardiac surgery: follow-up of a randomised clinical trial Introduction Acute kidney injury (AKI) is a common complication after cardiac surgical procedures and is associated with an increased morbidity and mortality.

Results

Conclusion