Long-term effects of interventional devascularization in treating cirrhosis patients with portal hypertension

Abstract

Objective To analyze long-term cumulative survival and re-bleeding rate of cirrhosis patients with portal hypertension after interventional devascularization and to evaluate long-term efficacy and importance of interventional devascularization. MethodsSixty-one cirrhosis patients with portal hypertension were retrospectively studied after interventional devascularization. The number of patients in Child A, B and C was respectively 25, 25 and 11, while that of mild, moderate and severe gastro-esophageal varices was 10, 31 and 20 respectively. Forty-seven patients had gastrointestinal bleeding history. Kaplan-Meier was used to analyze the long-term survival and re-bleeding rates, Log rank test was applied to measure differences in survival amaong the patients with different degree of hepatic function or gastro-esophageal varices, and Cox regression was used for multivariate analysis of survival, which had statistical significance with P 800 ml (OR=11. 024, P=0. 0003) before therapy were independent predictors of poor long-term survival. Conclusions Interventional devascularization providing good long-term efficacy for cirrhosis patients with portal hypertension was a useful treatment for these patients. Key words: Liver cirrhosis; Hypertension; portal; Radiology; interventional; Portasystemic shunt; Retrospective studies ; Treatment outcome