Abstract
Long-term multigeneration effects of the dietary intake of calcium carrageenan were measured in a three-generation reproduction and teratology study in Osborne-Mendel rats. Dietary levels of 0·5, 1·0, 2·5 or 5·0% were ingested throughout the study. Carrageenan ingestion caused dose-related and significant decreases in the weights of offspring at weaning, but no effects were detected in respect of fertility, average litter size, average number of liveborn animals, viability or survival of offspring.
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