Abstract

Bacharier LB, Raissy HH, Wilson L, McWilliams B, Strunk RC, Kelly HW. Pediatrics . 2004;113:1693–1699 To determine the safety of 36 months of inhaled budesonide administration on hypothalamic-pituitary-adrenal (HPA) axis function in children with mild to moderate asthma. Sixty-three children enrolled in the previously published Childhood Asthma Management Program (CAMP) study with mild to moderate asthma (mean age: 9.5 ± 1.9 years). CAMP participants were between 5 and 12 years of age. Children received placebo, nedocromil (16 mg/day by metered-dose inhaler), or budesonide (400 μg/day by Turbuhaler). HPA axis function was assessed at baseline and after 12 and 36 …

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