Abstract
According to the International Diabetes Federation (IDF), the number of patients with diabetes in the world reached 463 million people in 2019. One of the most severe local complications of diabetes is diabetic foot syndrome manifested through the development of diabetic ulcers on the lower extremities, which leads to poor quality of life and disability.
Highlights
According to WHO and the International Diabetes Federation (IDF), the number of patients with diabetes in the world reached 425 million people in 2017. 727 billion US dollars were spent on the treatment of diabetes mellitus and its complications worldwide [1]
It was found that the recurrence of ulceration in the main group of subjects occurred less frequently, as compared with patients in the comparison group (p
33 (70.2%) subjects could participate in normal daily activities vs. 17 (37.8%) subjects in the comparison group
Summary
According to WHO and the International Diabetes Federation (IDF), the number of patients with diabetes in the world reached 425 million people in 2017. 727 billion US dollars were spent on the treatment of diabetes mellitus and its complications worldwide [1]. According to WHO and the International Diabetes Federation (IDF), the number of patients with diabetes in the world reached 425 million people in 2017. 727 billion US dollars were spent on the treatment of diabetes mellitus and its complications worldwide [1]. The disease is usually accompanied by a substantial number of general and local complications, which lead to disability and mortality [8]. One of the local severe complications of DM is diabetic foot syndrome. 16-18% of patients with diabetes develop ulcerative defects of the lower extremities, and the treatment requires significant effort, time, and economic costs. Autologous platelet-rich plasma (APRP) has been tested for the treatment of trophic ulcers. Platelets are thought to initiate wound healing by releasing local growth factors that activate reparative processes in tissues [3, 4]
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