Abstract
BackgroundBiochemical control from series in which radical prostatectomy is performed for patients with unfavorable prostate cancer and/or low dose external beam radiation therapy are given remains suboptimal.The treatment regimen of HDR brachytherapy and external beam radiotherapy is a safe and very effective treatment for patients with high risk localized prostate cancer with excellent biochemical control and low toxicity.
Highlights
Patients with clinical stage T1c, Gleason score sum 6 tumors, and prostate-specific antigen (PSA) values < 10 ng/ml have a high likelihood of disease-free survival, regardless of the treatment option chosen.we are faced with a great dilemma when we seen newly diagnosed patients with high-risk prostate cancer
One approach was a combination of external beam radiotherapy (EBRT) with an intensity modulated with high dose rate (HDR) prostate brachytherapy boost
Clinical characteristics All patients treated in the protocol were included for analysis and completed the planned course of radiation
Summary
We are faced with a great dilemma when we seen newly diagnosed patients with high-risk prostate cancer. Results of conventionally accepted therapies such as radical prostatectomy and/or standard radiotherapy have not provided these patients with good outcomes [1,2,3]. One approach was a combination of external beam radiotherapy (EBRT) with an intensity modulated with high dose rate (HDR) prostate brachytherapy boost. Biochemical control from series in which radical prostatectomy is performed for patients with unfavorable prostate cancer and/or low dose external beam radiation therapy are given remains suboptimal. The treatment regimen of HDR brachytherapy and external beam radiotherapy is a safe and very effective treatment for patients with high risk localized prostate cancer with excellent biochemical control and low toxicity
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