Abstract

Long-Term Adaptations to Aerobic-Anaerobic Physical Training in the Erythrocyte Membrane Fatty Acids Profile

Highlights

  • Fatty acids are critical organic compounds involved in the synthesis of other lipids like phospholipids and glycolipids constituting lipid bilayer of all cell membranes, besides they are an important source of chemical energy [1]

  • This work aims to evaluate the long-term effect of aerobic-anaerobic exercise on basal erythrocyte fatty acid concentrations in both Trained (TG) and Untrained (UG) and participants, and to identify the possible relationship existing between the properties of the erythrocyte membrane and the degree of training

  • The results show a difference (p < 0.01) in the short chain fatty acid lauric acid (12:0) between the Trained Group (TG) and the Untrained Group (UG), with much higher concentrations in the TG

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Summary

Introduction

Fatty acids are critical organic compounds involved in the synthesis of other lipids like phospholipids and glycolipids constituting lipid bilayer of all cell membranes, besides they are an important source of chemical energy [1]. High concentrations of saturated fatty acids can convey harmful effects, whereas unsaturated fatty acids may develop a protective role [3,4]. They are considered an attractive target to regulate the human diseases of obesity, diabetes, cancer, cardiovascular complications and inflammatory processes [5,6]. Fatty acids half-life in adipose tissues is estimated to last 680 days, while erythrocyte half-life is of around 120 days. To reflect long-term adaptations, erythrocytes are a more suitable organic matrix than plasma [7,8,9,10,11]

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