Long-standing Vulvar Pruritus

Abstract

A number of additional tests were performed: serology, which was negative for human immunodeficiency virus, hepatitis C virus, hepatitis B virus, and syphilis; culture of the vaginal discharge, which was positive for Candida albicans; and biopsy of 1 of the lesions. Histology revealed skin from the genital region with a superficial erosion occupied by fibrin deposits, marked regenerative changes at the borders, and a dense linear infiltrate in the upper dermis (Figure 2), composed mainly of plasma cells (Figure 3); there were no other apparent changes. Immunohistochemical analysis of the biopsy was performed and was negative for treponemes.