Abstract
The long-range correlations within the current signal time series of the Beta vulgaris vacuolar membrane under the influence of organolead compound (Met3PbCl) are investigated. The current time series is transformed into a dwell time series. Then the rescaled range and detrended fluctuations analyses are used. It is shown that the presence of Met3PbCl in the solution decreases the mean value of the Hurst exponent and therefore influences the long-range correlations in ionic channel current. This observation is statistically significant. An ion channel model is built and the experimental results reconstructed and analysed.
Highlights
This paper is the continuation of the researches on the ionic current influenced by organolead compounds [1]
The ionic time series were registered by the patch-clamp technique and subsequently transformed into the dichotomous signal, which was converted into the dwell time series
The transformed series were investigated by range analysis (R/S) and detrended fluctuation analysis (DFA) analyses
Summary
This paper is the continuation of the researches on the ionic current influenced by organolead compounds [1]. Lead was reported as being the second most hazardous substance, after arsenic, based on the frequency of occurrence, toxicity, and the potential for human exposure by the Agency for Toxic Substances and Disease Registry [12]. Both acute and chronic lead exposure has the potential to cause many serious systematic effects in people including hypertension, anaemia, immune imbalances, infertility, cognitive deficits, adverse effects on nervous and renal systems, delayed skeletal and deciduous dental development, vitamin D deficiency, and gastrointestinal effects [13].
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