Abstract
Current optical coherence tomography (OCT) imaging suffers from short ranging distance and narrow imaging field of view (FOV). There is growing interest in searching for solutions to these limitations in order to expand further in vivo OCT applications. This paper describes a solution where we utilize an akinetic swept source for OCT implementation to enable ~10 cm ranging distance, associated with the use of a wide-angle camera lens in the sample arm to provide a FOV of ~20 x 20 cm2. The akinetic swept source operates at 1300 nm central wavelength with a bandwidth of 100 nm. We propose an adaptive calibration procedure to the programmable akinetic light source so that the sensitivity of the OCT system over ~10 cm ranging distance is substantially improved for imaging of large volume samples. We demonstrate the proposed swept source OCT system for in vivo imaging of entire human hands and faces with an unprecedented FOV (up to 400 cm2). The capability of large-volume OCT imaging with ultra-long ranging and ultra-wide FOV is expected to bring new opportunities for in vivo biomedical applications.
Highlights
First introduced in 1991 [1], optical coherence tomography (OCT) has been amply demonstrated as a powerful inspective tool due to its capability of depth-resolved imaging with high resolution [2]
In order to overcome the limitation of the point spread function (PSF) roll-off and improve the overall imaging sensitivity over the entire ranging depth, below we introduce an adaptive calibration procedure in the post-processing of OCT signals
3.1 Assessment of OCT system performance after adaptive calibration To assess the system sensitivity performance over the entire ranging distance after the adaptive calibration procedure described in the last section, a mirror was installed in the sample arm, and the roll-off curve of the system point spread function (PSF) was measured by varying the optical path length in the reference arm
Summary
First introduced in 1991 [1], optical coherence tomography (OCT) has been amply demonstrated as a powerful inspective tool due to its capability of depth-resolved imaging with high resolution [2]. These advantages of this akinetic swept source provide opportunities for developing an OCT system that can deliver ultra-long ranging distance and ultra-wide FOV imaging.
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