Abstract

Recent studies show that some long non-coding RNA (lncRNA) is specifically expressed in leukemia with mixed lineage leukemia (MLL)-rearranged, BCR-ABL, promyelocytic leukemia-retinoic acid receptor α (PML-RARα), and acute myeloid leukemia 1 (AML1)-ETO fusion gene, which is closely related to the occurrence, development and prognosis of leukemia. Specifically expressed lncRNA may provide new strategies for the diagnosis and treatment, which may provide a guidance for clinical prognosis of leukemia. Key words: Leukemia; Karyotype; Long non-coding RNA

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