Abstract

Background and Aims : FCS is a rare autosomal recessive disorder of impaired lipoprotein lipase (LPL) function, elevated TG levels, abdominal pain and pancreatitis. Current treatment (extremely low-fat diet <10% fat/day to reduce TG levels ≤750mgldL) is ineffective. Lomitapide is a microsomal triglyceride transfer protein (MTP) inhibitor that reduces circulating levels of TGs.

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