Abstract

To investigate potential prognostic factors and to predict extent of risks for postoperative pulmonary complications by logistic regressive analysis, and to evaluate the role of non-invasive ventilation in reducing the incidence of complications in elderly patients. A stair-climbing test was carried out with ASA score, FEV1, changes of SpO2 and HR noted at the same time. Logistical regressive analysis based on these parameters were used to assess the relation between potential prognostic factors and postoperative complications. Patients with limited pulmonary reserves were selected using the equation, and the protective effect of non-invasive ventilation on these patients was assessed. The incidence of postoperative pulmonary complications for high-risk patients with non-invasive ventilation was 33.2%, and the incidence of pulmonary complications for high-risk patients without non-invasive ventilation was 67.7%. There was not a significant difference between these two groups with low-risk (P > 0.05). The mathematical model of logistic regressive analysis using the stair-climbing testing combined with other parameters is a simple, reliable method to predict the cardiopulmonary reserved function in elderly patients. Non-invasive ventilation can effectively reduce the incidence of postoperative pulmonary complications for high-risk patients, but it has no effect on patients with low risk.

Highlights

  • Community-acquired pneumonia remains a common ventilation (MV) were randomized into two groups: one group was condition worldwide

  • This study shows that the inhibition of the intramyocardial expression of tumour necrosis factor (TNF)-α and of its secondary mediator COX-2 related to moderate hypothermia during cardiopulmonary bypass (CPB) is associated with the inhibition of p38 mitogen-activated protein kinase (MAPK)–acute pancreatitis (AP)-1, but not of the NF-κB pathway

  • Purification, characterization, and analytical mass assignment of inducible nitric oxide synthase (iNOS) from DLD-1-5B2 cells are in progress to provide mass standardization for the iNOS immunoassay

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Summary

Introduction

Community-acquired pneumonia remains a common ventilation (MV) were randomized into two groups: one group was condition worldwide. Methods Eighty-one consecutive patients (age 63 ± 16 years, male n = 51, SAPS 2 score 49 ± 11, mechanical ventilation n = 50, vasopressors n = 56, renal failure n = 19, postoperative n = 23) admitted to the ICU during a 3-month period were evaluated. Probiotics administration was suggested to reduce the incidence of infections and the overall morbidity and mortality in surgical patients The aim of this prospective randomized clinical trial was to assess the effects of a combination formula of probiotics and prebiotics (Synbiotic 2000Forte; Medifarm, Sweden) versus prebiotics only (fiber) in critically ill, long-term mechanically ventilated trauma patients. This study examines the acute patient outcomes associated with the evolution of early total care to damage control orthopaedics for multiply injured patients with femoral shaft fractures

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