Locoregional Patterns of Failure in Oropharyngeal Carcinoma: Implications for Treatment De-escalation

Abstract

Factor n Site BOT 16 Tonsil 12 T Stage T1 3 T2 14 T3 4 T4 7 N Stage N0 3 N1 2 N2 21 N3 2 CONCLUSIONS MATERIALS/METHODS Loco-regional failure (LRF) in oropharyngeal carcinoma (OPC) has dropped markedly in the past decade. Improved outcomes have led many investigators to seek methods for deescalating treatment. We examined our patterns of LRF to identify areas at low risk for isolated failure, which could be considered for dose de-escalation • 85% of local failures (LF) (17/20) were in the center of the PTV70Gy