Abstract

A phage lambda gene, called tof, responsible for the turnoff of λ-exonuclease synthesis during the lytic cycle has been located in the region of the lambda genome which is nonhomologous with the λi 434 genome. The corresponding region of the λi 434 genome also contains a tof gene whose product turns off the synthesis of λ-exonuclease during the lytic cycle of phage λi 434. The site of action of both tof gene products is also located in the region of nonhomology between the two phage genomes.

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