LOCALIZED VOCAL CORD AMYLOIDOSIS

Ayşe Cefle,Ayten Yazıcı,Kürşat Yıldız,Kazım Sepetçigil

doi:10.29333/ejgm/82426

Ayşe Cefle, Ayten Yazıcı + Show 2 more

Open Access

https://doi.org/10.29333/ejgm/82426

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Abstract

Kocaeli University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Internal Medicine and Pathology. Kocaeli, Turkey Localized laryngeal amyloidosis is an uncommon diease with limited long-term follow- up studies. The precise etiology and pathogenesis are not entirely clear. We present a case of localized laryngeal amyloidosis. 35 years old man suffered from hoarseness during the last six months. Laryngoscopic examination showed nodular infiltration of bilateral vocal cords. Amyloidosis was confirmed by the characteristic Congo red staining of biopsies. The search for other localizations of amyloidosis was negative. No evidence of systemic amyloidosis or plasma cell proliferation was found in this patient. There were no recurrences during the nine-months follow-up

Highlights

Amyloidosis is a disorder in which an insoluble proteinaceous material is deposited in the extracellular matrix of tissues
We are reporting a case of localized vocal cord amyloidosis in a 35 year old man
Amyloidosis is a generic term for a heterogeneous group of disorders associated with extracellular deposition of protein in an abnormal fibrillar form

Summary

LOCALIZED VOCAL CORD AMYLOIDOSIS

Kocaeli University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Internal Medicine and Pathology. Localized laryngeal amyloidosis is an uncommon diease with limited long-term followup studies. The precise etiology and pathogenesis are not entirely clear. We present a case of localized laryngeal amyloidosis. 35 years old man suffered from hoarseness during the last six months. Laryngoscopic examination showed nodular infiltration of bilateral vocal cords. Amyloidosis was confirmed by the characteristic Congo red staining of biopsies. The search for other localizations of amyloidosis was negative. No evidence of systemic amyloidosis or plasma cell proliferation was found in this patient. There were no recurrences during the nine-months follow-up

INTRODUCTION

DISCUSSION