Abstract

Introduction Type IV collagen is a major structural component of basement membrane (BM) and acts as a scaffold for other BM constituents. It is a heterotrimeric molecule that exists in six genetically distinct forms, α1(IV) α6(IV). The ameloblastoma is the most frequently encountered odontogenic epithelial tumor. The BM zone of the ameloblastoma remains a subject of research interest primarily because of increasing evidence of its mediatory role during oncogenesis. However, the expression pattern of specific collagen α (IV) chains in the ameloblastoma BM has not been previously reported. In this preliminary study, indirect immunofluorescence was utilized to localize α1(IV) α6(IV) chains in the BM of two

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