Abstract
Immune complexes of horseradish peroxidase (HRP) and rabbit IgG antibodies to HRP were used to study the Fc gamma receptors in the human central nervous system (CNS). The peroxidase activity was demonstrated with 3,3'-diaminobenzidine tetrahydrochloride and H2O2. The majority of the pia and arachnoid cells of the leptomeninges, the stroma cells of the arachnoid granulations and the adventitial cells in the perivascular spaces of the nervous tissue were stained. The villi of the choroid plexus were also stained. By electron microscopy the reaction products were localized to the plasma membranes of the stroma cells and at the basal aspects of the epithelial cells in the choroid villi. In addition, reaction product was demonstrated on pericytes of some of the brain capillaries. The immune complexes did not bind to the brain parenchyma.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
