Abstract
Dystrophin is a protein present in normal human muscle but absent in patients with Duchenne muscular dystrophy (DMD). Using a specific antibody, we have investigated the expression of dystrophin in human muscle which had regenerated in culture in the presence of nerve cells. Dystrophin was present and was correctly localized in the cultures of normal muscle but was absent from cultures of muscle from patients with DMD. Its control and function can now be studied.
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