Abstract
SUMMARY A direct study of the complement-fixing reactivity of cell membranes, soluble components of cell membranes and cell interiors of lymphoblast cell lines showed that with highly concentrated levels of antigen, complement-fixing reactivity could be measured consistently between the cell interior of lymphoma (IM1), leukaemic (4265) and Burkitt lymphoma (P3) cultured cells and sera from patients with infectious mononucleosis or Burkitt lymphoma. A measurable complement-fixing reactive cell-membrane antigen appeared to be present in IM1 and 4265 cells. Complement-fixing activity was also recovered in a soluble fraction of 4265 cell membranes after sonication and separation by Sephadex gel filtration. Separation of the complement-fixing reactive component from HL-A antigens was achieved by gel electrophoresis.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
