Abstract

The book starts with a chapter on historical aspects concerning cerebral localization. The application of modern neuroimaging and cognate techniques has re-evaluated the meaning of `localization'. The complicated concept of interhemispheric interaction and integration is emphasized. Two chapters deal with corpus callosum agenesis and its influence on hemispheric specialization and interhemispheric communication. The congenital absence of corpus callosum in children is not related to the severe disconnection syndrome seen in commissurotomized adults, which points to the great potential for cerebral plasticity and re-organization of the young brain. The compensation, however, is not complete. This is also valid for acquired lesions of the corpus callosum in children and adolescents. One chapter deals with language and neuropsychological dysfunction in basal ganglia lesions. Interesting information is provided concerning the cortico-striato-pallido-thalamo-cortical loops subserving multiple functions. Some of them have an activating or …

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