Abstract
By using a visual method of presenting DNA sequences (Makino, S., Amano, N., and Suzuki, M., 1999, Proc. Japan Acad. 75B, 311-316), genomic sequences of various organisms have been analyzed, including of a draft sequence of human genome (International Human Genome Sequencing Consortium, 2001, Nature 409, 860-921). It is concluded that, with an increase in the number of basepairs in a genome, a tendency becomes clearer for clustering of A:T pairs and G:C pairs separately into regions of 0.5-5K basepairs in length. It is likely that these regions have important functions for regulating transcription of the increasing number of genes coded and for organizing replication of the increasing length of genomic DNA.
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