Abstract
A study of acute pharyngeal infections treated by the topical application of sulfathiazole powder in the otolaryngologic dispensary of St. Luke's Hospital is presented here. Sulfathiazole (2-[paraaminobenzenesulfonamido]-thiazole) is the thiazole analogue of sulfapyridine (2-[paraaminobenzenesulfonamido]-pyridine) and was first reported on by Fosbinder and Walker 1 and by Lott and Bergeim. 2 These authors described the methods of preparation and their experiments with these drugs against streptococcic and pneumococcic infections in mice. The original work on the physical and chemical characteristics of sulfathiazole and its salt was done at that time, and tests for the estimation of the drug in the body were described. Van Dyke and his co-workers 3 showed the rapid metabolism of this drug in the body. Sulfathiazole was proved to be more rapidly absorbed than other sulfanilamide derivatives, the concentration in the blood reaching its highest level in one to three hours after ingestion of the drug. Moreover, it disappeared and
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Archives of Otolaryngology - Head and Neck Surgery
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
