Abstract

We consider the following question on the relationship between the asymptotic behaviors of asynchronous dynamics of Boolean networks and their regulatory structures: Does the presence of a cyclic a...

Highlights

  • Boolean networks are used to model the dynamics resulting from the interactions between n regulatory components that can assume only two values, 0 and 1, and are naturally described as maps from {0, 1}n to itself

  • We describe how Question 1.1 can be translated into a Boolean satisfiability problem (SAT)

  • We show that the problem can be approached as a Boolean satisfiability problem, and find that all maps from

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Summary

Introduction

Boolean networks are used to model the dynamics resulting from the interactions between n regulatory components that can assume only two values, 0 and 1, and are naturally described as maps from {0, 1}n to itself. Regulatory graph, local negative circuits, cyclic attractors, asynchronous dynamics Does the absence of fixed points imply the existence of a local negative circuit in the regulatory graph?

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