Abstract
The central inhibitory effect of systemic hypoxia on respiration can be explained by different mechanisms including withdrawal of excitatory inputs to respiratory related neurons. It has been shown that several groups of catecholamine containing neurons, including the locus ceruleus (LC), express chemosensitive properties. Different stimuli like hypercapnia, hypoxia or electrical stimulation of carotid sinus nerve, induce c-fos protein expression in the LC neurons.1,2 Furthermore, their activation by increased hydrogen ions causes elevation of respiratory drive.3 KeywordsExcitatory InputRespiratory DriveLocus CeruleusNucleus LocusSodium CyanideThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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