Abstract
In the cow, persistence of the cl follows complete or partial hysterectomy (Wiltbank & Casida, 1956; Anderson, Neal & Melampy, 1962), whereas the oestrous cycle is shortened by endometrial inflammation (Kendrick & McEntee, 1967; Nakahara, Domeki, Inui & Yamauchi, 1967) or by uterine distension with an IUD (Yamauchi & Nakahara, 1958; Hansel & Wagner, 1960) or a gel-like substance (Yamauchi, Nakahara, Kaneda & Inui, 1967). Experiments involving unilateral hysterectomy of the cow have shown that the cl in the ovary adjacent to the remaining uterine horn regressed earlier than that in the opposite ovary (Ginther, Woody, Mahajan, Janakiraman & Casida, 1967). Similar local uterine effects on the cl have been observed following uterine distension (Ginther, Woody, Janakiraman & Casida, 1966). The present study was undertaken to investigate the local inhibitory effects of endometrial inflammation induced by iodine solution on luteal function in the cow. The experiments were conducted to determine: ( 1 ) the relation between the dose of iodine solution and the area of endometrial inflammation, (2) the minimum effective dose of iodine solution for modifying the luteal function, and (3) the unilateral effect of endometrial inflammation on the life-span ofthe
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