Abstract

Infrared (IR) therapy is used for pain relief in patients with knee osteoarthritis (OA). However, IR's effects on the cardiovascular system remain uncertain. Therefore, we investigated the local and systemic cardiovascular effects of monochromatic IR therapy on patients with knee OA in a double-blind, randomized, placebo-controlled study. Seventy-one subjects with knee OA received one session of 40 min of active or placebo monochromatic IR treatment (with power output of 6.24 W, wavelength of 890 nm, power density of 34.7 mW/cm2 for 40 min, total energy of 41.6 J/cm2 per knee per session) over the knee joints. Heart rate, blood pressure, and knee arterial blood flow velocity were periodically assessed at the baseline, during, and after treatment. Data were analyzed by repeated-measure analysis of covariance. Compared to baseline, there were no statistically significant group x time interaction effects between the 2 groups for heart rate (P = 0.160), blood pressure (systolic blood pressure: P = 0.861; diastolic blood pressure: P = 0.757), or mean arterial blood flow velocity (P = 0.769) in follow-up assessments. The present study revealed that although there was no increase of knee arterial blood flow velocity, monochromatic IR therapy produced no detrimental systemic cardiovascular effects.

Highlights

  • Osteoarthritis (OA) generally involves articular cartilage, anabolic and catabolic mechanisms, and bony structures in the synovial joints [1]

  • The present study revealed that there was no increase of knee arterial blood flow velocity, monochromatic IR therapy produced no detrimental systemic cardiovascular effects

  • There was no statistically significant difference in the 2 groups in age, gender, educational level, marital status, occupation, comorbidities, smoking and drinking habits, body mass index (BMI), or severity of knee OA according to the Kellgren-Lawrence scores and WOMAC assessments

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Summary

Introduction

Osteoarthritis (OA) generally involves articular cartilage, anabolic and catabolic mechanisms, and bony structures in the synovial joints [1]. Pain and decreased postural stability may be accompanied by difficulties in performing basic and instrumental daily activities, increased fall risks among community-dwelling elderly [3, 4], and a decreased quality of life [5]. Physical modalities are commonly used to treat older patients with knee OA to ameliorate pain and improve functional performance in the rehabilitation medical field. Physical modalities, such as hot packs, pulse ultrasound, transcutaneous electrical nerve stimulation, and phototherapy, are commonly applied to patients with musculoskeletal pain to increase local circulation [6]. There are few high-quality clinical studies with randomized placebocontrolled designs on physical modalities’ therapeutic effects in the rehabilitation medicine field [7]

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