Abstract
Local and Locoregional Disease Free Survival in Patients Receiving NSM or SSM Compared with Conventional Mastectomy
Highlights
In this study we evaluated local recurrence-free survival (LRFS) and locoregional recurrence-free survival (LRRFS) for women at our institution who received nipple sparing mastectomy (NSM) and SSM as compared to patients receiving traditional non-skin or nipple sparing mastectomies (TM)
Mean tumor size tended to be smaller in NSM patients (1.16 cm compared with 1.48 cm for SSM and 1.71 cm for traditional mastectomy (TM), p = 0.03)
There were no significant differences in T-stage, multifocality, lymphovascular space invasion (LVSI), grade, margin status, race, tobacco usage, use of hormone or chemotherapy, hormone receptor status, and human epidermal growth factor (HER2) receptor status between the 3 groups
Summary
In this study we evaluated local recurrence-free survival (LRFS) and locoregional recurrence-free survival (LRRFS) for women at our institution who received NSM and SSM as compared to patients receiving traditional non-skin or nipple sparing mastectomies (TM). At eight years LRRFS was 94.3% for TM, 92.6% for NSM and 91.4% for SSM with no significant differences seen among these groups (p = 0.51). Over the last 15 years, techniques to improve cosmetic outcomes by preserving the skin and nipple overlying the breast have been pioneered. These techniques include: skin-sparing mastectomy (SSM) where the breast tissue and the nipple areolar complex (NAC) are removed but the skin overlying the breast is preserved, and the nipple sparing mastectomy (NSM), where the skin and NAC are preserved[3,5,6,7,8]. Preserving the skin in an SSM and the preservation of the NAC in the NSM results in better cosmesis, improved patient satisfaction, and quality of life[3,5,8,9]
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