Abstract
Imiquimod (INN) can cause chemical injury in the oral mucosa, leading to local irritation, including erythema, ulceration, and pain. We report a case of a 34-year-old male patient presenting a symptomatic lesion on the lower and upper lip mucosa. The patient reported that the lesion appeared after applying INN 5% cream prescribed by a dermatologist as treatment for a white, plaque-shaped, asymptomatic lower lip lesion. Clinically, the lesion presented redness and extensive ulceration and erosion area, which extended throughout the upper and lower labial mucosa. Therefore, the diagnostic hypothesis of chemical injury induced by topical INN was considered. Request for INN suspension and prescription of oral prednisone and topical clobetasol propionate were made. After 3 weeks, total lesion resolution was observed. Thus, we highlight that topical INN can cause local adverse effects, and an effective diagnosis is of utmost importance to promote adequate treatment.
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