Lizards as models to explore the ecological and neuroanatomical correlates of miniaturization

Abstract

Abstract Extreme body size reductions bring about unorthodox anatomical arrangements and novel ways in which animals interact with the environment. Drawing from studies of vertebrates and invertebrates, we provide a theoretical framework for miniaturization to inform hypotheses using lizards as a study system. Through this approach, we demonstrate the repeated evolution of miniaturization across 11 families and a tendency for miniaturized species to occupy terrestrial microhabitats, possibly driven by physiological constraints. Differences in gross brain morphology between two gecko species demonstrate a proportionally larger telencephalon and smaller olfactory bulbs in the miniaturized species, though more data are needed to generalize this trend. Our study brings into light the potential contributions of miniaturized lizards to explain patterns of body size evolution and its impact on ecology and neuroanatomy. In addition, our findings reveal the need to study the natural history of miniaturized species, particularly in relation to their sensory and physiological ecology.