Liver transplant pathology

Abstract

A 61-year-old man underwent liver transplantation for alcoholic cirrhosis. The initial postoperative period was uneventful. During the second week he developed worsening liver biochemistry: aspartate transaminase (AST) 139 U/l (normal 5–43), alkaline phosphatase (ALP) 2048 U/l (normal 70–330), bilirubin 172mmol/l (normal 1–22). A liver biopsy was taken on day 15. Fig. 1(a,b) shows representative changes in portal tracts. Fig. 1(c,d) illustrates changes occurring in zone 3 of the liver parenchyma.