Liver function: an attempt to correlate structural change with functional abnormality.

Abstract

Article1 November 1951LIVER FUNCTION: AN ATTEMPT TO CORRELATE STRUCTURAL CHANGE WITH FUNCTIONAL ABNORMALITYJOHN W. NORCROSS, M.D., F.A.C.P., JOSEPH D. FELDMAN, M.D., ROBERT F. BRADLEY JR., M.D., ROBERT M. WHITE, M.D.JOHN W. NORCROSS, M.D., F.A.C.P.Search for more papers by this author, JOSEPH D. FELDMAN, M.D.Search for more papers by this author, ROBERT F. BRADLEY JR., M.D.Search for more papers by this author, ROBERT M. WHITE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-35-5-1110 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn recent years some attempt has been made to correlate liver function tests with the histologic changes seen in liver biopsies, most of which have been obtained by the aspiration method.Sherlock1in 1946 compared degrees of liver cell damage with various liver function test abnormalities and noted few significant correlations. Franklin et al.2in 1948 reported some association of diffuse liver cell damage and abnormal function tests. In a later work, Popper et al.3showed a further quantitative correlation between the severity of damage and the degree of function test abnormality. Kinsell et al.4in a small series of...Bibliography1. 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Author, Article, and Disclosure InformationAffiliations: *Received for publication August 16, 1950.From the Department of Internal Medicine, the Lahey Clinic, and the Department of Pathology, New England Deaconess Hospital, Boston, Massachusetts. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInterpretation of the Liver BiopsyEvaluation of hepatic dysfunctionLiver function tests in obstructive jaundice 1 November 1951Volume 35, Issue 5Page: 1110-1116KeywordsBiopsyHospital medicineLiverLiver function tests ePublished: 1 December 2008 Issue Published: 1 November 1951 PDF downloadLoading ...