Abstract
<h3>To the Editor.—</h3> In a recent CASE REPORT, D'Silva et al (1982;248:1495) describe disseminated aspergillosis occurring in a patient who was presumably immunocompetent. This patient had a history of excessive alcohol intake, icterus on admission, increased prothrombin time, and elevated liver enzyme levels. Autopsy findings did not reveal features of cirrhosis or alcoholic hepatitis; focal abscesses in the liver containing hyphae of<i>Aspergillus</i>were seen. On the basis of these findings, the authors surmise that the<i>Aspergillus</i>microabscesses probably accounted for the altered liver function study results. Autopsy findings also showed a moderate degree of fatty metamorphosis and areas of centrilobular congestion and necrosis unrelated to the<i>Aspergillus</i>abscesses. In view of these findings, an alternate possibility— that liver injury predisposed to asperillosis—certainly exists. Further support for this possibility is found in the literature. A review of the literature revealed four cases of disseminated aspergillosis occurring in patients with liver
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