Abstract
During an outbreak of Q fever in Germany, we identified an infected sheep flock from which animals were routinely used as a source for life cell therapy (LCT), the injection of fetal cells or cell extracts from sheep into humans. Q fever developed in 7 LCT recipients from Canada, Germany, and the United States.
Highlights
During an outbreak of Q fever in Germany, we identified an infected sheep flock from which animals were routinely used as a source for life cell therapy (LCT), the injection of fetal cells or cell extracts from sheep into humans
Q fever developed in 7 live cell therapy (LCT) recipients from Canada, Germany, and the United States
On August 12, five of 8 patients tested by ELISA and immunofluorescence test (IFT) by the local health department had results consistent with acute C. burnetii infection
Summary
During an outbreak of Q fever in Germany, we identified an infected sheep flock from which animals were routinely used as a source for life cell therapy (LCT), the injection of fetal cells or cell extracts from sheep into humans. Q fever developed in 7 LCT recipients from Canada, Germany, and the United States. Human patients show signs and symptoms, such as fever, severe headache, nausea, pneumonia, or hepatitis, 2-3 weeks after infection.
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