Abstract

Background: Saliva is a versatile biofluid that can help in detecting any oral or systemic disease of an individual. Saliva seems to be clinically an informative biofluid for easy prognosis of a disease and clinical or laboratory diagnosis of oral as well as many systemic diseases. It has some specific soluble biological markers that can be considered as an ideal approach for early detection of diseases.
 Aim: The aim of this paper was to review the recent developments of the Lite Image Analysis Module.
 Conclusion: Thus, this technology primarily helps in a rapid assessment of salivary biomarker levels signifying the probable systemic and oral condition of an individual both in quantitative as well as qualitative manner. Adopting a simple and quick technique, LIAM can be used effortlessly in some rural remote areas as well where advanced high technology laboratories have not yet reached.
 Clinical Significance: It is one of the recent advancements in the world of salivary diagnosis LIAM (Lite Image Analysis Module) that is a portable, light, hand-held scanning device which magnificently integrates a distinct analyte identification system that detects the type of analytes being tested and transfer the report straight to a smartphone or a Bluetooth devices.

Highlights

  • Phase detection of human diseases like cancer, cardiovascular and metabolic disorders turns out to be a challenging situation in a healthcare setting

  • Saliva seems to be clinically an informative biofluid for easy prognosis of a disease and clinical or laboratory diagnosis of oral as well as many systemic diseases. It has some specific soluble biological markers that can be considered as an ideal approach for early detection of diseases

  • Conclusion: this technology primarily helps in a rapid assessment of salivary biomarker levels signifying the probable systemic and oral condition of an individual both in quantitative as well as qualitative manner

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Summary

INTRODUCTION

Phase detection of human diseases like cancer, cardiovascular and metabolic disorders turns out to be a challenging situation in a healthcare setting. Reports gradually flourished that the parotid saliva flow rate relies on different factors such as nervousness, morality, judgement and introversion [3] As it is known, saliva reflects the body’s health as it comprises hormones, proteins, enzymes which are often present in standard blood tests to identify any disease. Most of the times it turns out to be a challenge to diagnose any systemic disorder without the use of additional invasive investigations To tackle these conditions, medical experts are identifying disease biomarkers which are non-invasive and will give a quick diagnosis of any condition. As previously mentioned unlike blood, salivary diagnostics offers a simple, cheap, atraumatic and stress-free procedure for disease detection as biomarkers [9] present in the saliva can be very useful for early detection of disorder to prevent harmful consequences. There is a decrease in the level of salivary amylase and carbonic anhydrase [10]

Sarcoidosis
Dental Caries and Periodontal Diseases
Malignancy
Psychological Condition
Drug Level Monitoring
Forensics
Viral Infection
1.10 Bacterial Infections
Benefits of Liam
Equipment of Liam Module
Processing of the Sample
FUTURE INVESTIGATIONS
RECENT ADVANCES IN LATERAL FLOW IMMUNOASSAY
CONCLUSION
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