Abstract
Cerebrospinal fluid (CSF) cytology and immunocytological studies were performed in 137 HIV-infected patients in stages WR3-WR6 with different neurologic symptoms. According to clinical, radiological and autoptic findings a diagnostic distribution in the groups of chronic HIV encephalitis (n = 80), opportunistic infections of the central nervous system with toxoplasmosis (n = 4), cytomegalovirus (n = 5), papovavirus (n = 4), cryptococcus (n = 1), primary CNS lymphoma (n = 2) and secondary CNS lymphoma (n = 5) was made. The CSF cytological examination, including immunocytology, was very helpful in diagnosing cryptococcal meningitis and lymphomatose meningeal involvement. Patients with chronic HIV encephalitis presented with an increase of immunodeficiency a decrease in cell count. Bleocytosis with granulocytes indicated an opportunistic CNS-infection, except for progressive multifocal leukencephalopathy, which was characterised by very low cell counts.
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