Abstract

In order to find a fast and reliable method for measurements of organic and aqueous liquid phases containing a- and b-emitters in mixtures we developed a method based on Liquid Scintillation Counting (LSC) using Quantulus Low Level Spectrometer. The use of low level LSC instead of g-spectroscopy allows reduced sample activity, shorter count rates and use of sample changer. This is of great advantage when many samples have to be measured during a short time period. The main nuclides of interest were 227Ac and 223Ra. 227Ac does not have any appropriate g-radiation, therefore measurements of the nuclei of interest must be based on a- and b-spectroscopy. In this study, it is shown that analyses of the radionuclidic purity of the liquid phases could be determined by a- and b-spectroscopy with Quantulus.

Highlights

  • In radiopharmacy the purity of the species involved is extreemly high both concerning the radioactive and the chemical compounds

  • In order to find a fast and reliable method for measurements of organic and aqueous liquid phases containing α- and β-emitters in mixtures we developed a method based on Liquid Scintillation Counting (LSC) using Quantulus Low Level Spectrometer

  • It is shown that analyses of the radionuclidic purity of the liquid phases could be determined by α- and β-spectroscopy with Quantulus

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Summary

Introduction

In radiopharmacy the purity of the species involved is extreemly high both concerning the radioactive and the chemical compounds. As a part of their work on developing new anticancer therapeutic agents, Algeta ASA is extracting radium from actinium. This work is a study of di-phosphonate extractant Dipex® supplied by Eichrom as a separation agent for radium and actinium. The use of low level LSC instead of γ-spectroscopy allows reduced sample activity, shorter count rates and use of sample changer. This is of great advantage when many samples have to be measured during a short time period

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