Abstract
Recent studies have shown that liquid-liquid phase separation (LLPS) organizes cellular biochemical reactions through the formation of membrane-less organelles. Cells are extremely crowded, with up to 40% of the cell volume taken up by macromolecules. This molecular crowding can strongly affect LLPS. Moreover, the intracellular environment is far from equilibrium due to many energy-dependent active processes. We sought to understand the influence of molecular crowding and active processes on LLPS by combining both experimental and computational studies of an engineered synthetic LLPS system.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
