Abstract
Liquid crystals are defined as the fourth state of matter forming between solid and liquid states. Earlier the applications of liquid crystals were confined to electronic instruments, but recent research findings suggest multiple applications of liquid crystals in biology and medicine. Here, the purpose of this review article is to discuss the potential biological impacts of liquid crystals in the diagnosis and prognosis of cancer along with the risk assessment. In this review, we also discussed the recent advances of liquid crystals in cancer biomarker detection and treatment in multiple cell line models. Cases reviewed here will demonstrate that cancer diagnostics based on the multidisciplinary technology and intriguingly utilization of liquid crystals may become an alternative to regular cancer detection methodologies. Additionally, we discussed the formidable challenges and problems in applying liquid crystal technologies. Solving these problems will require great effort and the way forward is through the multidisciplinary collaboration of physicists, biologists, chemists, material-scientists, clinicians, and engineers. The triumphant outcome of these liquid crystals and their applications in cancer research would be convenient testing for the detection of cancer and may result in treating the cancer patients non-invasively.
Highlights
Cancer is defined as uncontrolled division of abnormal cells, so early detection of cancer can significantly improve patient treatment outcome and saves lives
This review article summarizes the recent developments in the discovery of cancer biomarkers such as nucleic acids, proteins, and enzymes with an emphasis on Liquid crystals (LCs) and application of LCs for development of novel drugs for both detection and treatment of cancer
Even though much more work is needed to translate these multidisciplinary technologies into viable cancer diagnostics and treatment options, the exploration of new LC based technologies for advanced cancer diagnostics is gaining interest invariably
Summary
Cancer is defined as uncontrolled division of abnormal cells, so early detection of cancer can significantly improve patient treatment outcome and saves lives. In general LCs are widely used in television screens as LCD (liquid crystal display) display, in display media, and in personal computers [15]. Of LCs, few investigators used “the dependent properties of LCs” to differentiate the lipid bilayer to differentiate the lipid bilayer enveloped viruses and non-enveloped viruses [30], in the diagnosis enveloped viruses and non-enveloped viruses [30], in the diagnosis of sepsis [31] (Figure 3). We discuss the ongoing progress of liquid crystals in cancer biomarker. Discuss the ongoingtoprogress of liquid crystals cancer the biomarker detection andreview treatment.
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