Abstract

The retention and separation of some 12 polar aromatic compounds, some of them weak acids and ampholytes, have been studied on cation-exchange resins and a non-ionic macroporous styrene-divinylbenzene polymer. The effects of pH, counter-ions and ion-pairing reagents have been measured. Ammonium ions extend the absorption of weak acids (p K a above 8) to higher pH values on an ion-exchange resin. The porous polymer has more selectivity than the ion-exchange resins, but plate numbers are less. Gradient elution may be used with the porous polymer, but radical solvent changes affect the quality of the packing.

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