Liquid Chromatography-Mass Spectrometric Analyses of Potential Antioxidant Constituents from Zanthoxylum zanthoxyloides Leaves: Probing into the Role of Alkaloids

doi:10.26538/tjnpr/v4i10.26

Abstract

Highlights

Plants are a major source of phytochemicals such as alkaloids, phenols, polyphenols, tannins and terpenes.[1]
Based on the antioxidant activity guided liquid chromatography-mass spectrometry (LC-mass spectroscopy (MS)) dereplication process, we evaluated for the first time the antioxidant potential of the various Vacuum liquid chromatography (VLC) fractions of Z. zanthoxyloides leaves
This study investigated the chemical constituents of the n-butanol fractions using highperformance liquid chromatography coupled with mass spectrometry (HPLC-MS) technique

Summary

Introduction

Plants are a major source of phytochemicals such as alkaloids, phenols, polyphenols, tannins and terpenes.[1] Research on medicinal plants is centered on phytochemistry, pharmacognosy and horticulture.[2] Research in phytochemistry tends to characterize their possible bioactive compounds, by separating them and subjecting them to detailed structural study.[3,4] These compounds are valuable health-promoting phytoconstituents of herbal preparations and plants with variable biological activities.[2] As most of the medicinal plants are not preserved, suitable analytical techniques are being employed to maintain and preserve the quality of medicinal plants.[5] Reliable and robust methodology for the analysis of medicinal plant extracts is imperative for quality control as well as drug development of new molecules.[6] Several analytical procedures based on the liquid chromatographic technique have been developed for quality control of plant extracts.[7, 8] High performance liquid chromatographic (HPLC) method coupled with mass spectroscopy (MS) (LC-MS) is one of the Citation: Ayoka TO, Nwachukwun N, Ene AC, Igwe CU, Nnadi CO. Liquid Chromatography-Mass Spectrometric analyses of Potential Antioxidant Constituents from Zanthoxylum zanthoxyloides Leaves: Probing into the Role of Alkaloids. Trop J Nat Prod Res. 2020; 4(10):817823.

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Conclusion