Year-end Sale % OFF 
Abstract
BackgroundThe treatment for microcystic lymphatic malformation (LM) remains challenging. We describe the liposuction-like sclerotherapy technique, a new treatment for extensive microcystic LM.MethodsLM data was retrospectively reviewed. This study included patients with a microcystic LM component treated by liposuction-like technique with bleomycin sclerotherapy.ResultsBetween June 2016 and October 2019, 39 consecutive patients (male/female ratio: 21:18; mean age, 33.6 months; range: 5 months to 15 years) with microcystic LM were treated by liposuction-like sclerotherapy (LS-LS) technique. Fifty-six sessions of LS-LS were performed (mean of 1.44 sessions per patient; range: one to four sessions). Follow-up ranged 6-30 months (mean of 21 months). We observed no major complications. Transient minor complications included: postoperative noninfectious fever, vomiting, temporary skin edema, pigmentation, mild local depressions, and/or irregularities, and a small hyperpigmented scar at the incision. No postoperative infection, skin ulcer, or necrosis occurred. The patients’ symptoms were successfully resolved or stable. A sub-complete response and partial response were observed for 26 (76%) and 13 patients (33%), respectively.ConclusionThe LS-LS technique for microcystic LMs is safe, feasible, and effective. This technique is an effective intervention with which it is possible to manage and potentially cure microcystic LM clinically.
Highlights
Lymphatic malformations (LMs) are congenital lymphatic anomalies, which may result from abnormal lymphatics development, often with underlying somatic PIK3CA mutation [1]
Between June 2016 and October 2019, 39 consecutive patients with microcystic LM were treated by liposuction-like sclerotherapy (LS-LS) technique
Encouraging results were obtained in microcystic LMs with intralesional bleomycin sclerotherapy [4-7]
Summary
Lymphatic malformations (LMs) are congenital lymphatic anomalies, which may result from abnormal lymphatics development, often with underlying somatic PIK3CA mutation [1]. LMs can be solitary or multifocal and can be classified into macrocystic ( 1-2 cm), microcystic ( 1 cm), or mixed cystic lesions [2]. Sclerotherapy is the mainstay treatment for macrocystic LMs but has a poor response in microcystic and mixed cystic lesions [3-5]. The microcystic lesion typically consists of multiple small cysts ( 1 cm), in which traditional sclerotherapy and direct injection are less effective due to the small size of the lumen. In cases with extensive microcystic component, it is difficult to obtain successful results despite multiple sclerotherapy sessions with traditional techniques. We have reported a new treatment, liposuction-like sclerotherapy technique (LS-LS) that successfully managed superficial LM in some cases [8]. We describe the liposuction-like sclerotherapy technique, a new treatment for extensive microcystic LM
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
