Abstract
Lipoprotein(a), type 2 diabetes and nephropathy; the mystery continues
Highlights
Implication for health policy/practice/research/medical education: Studies suggested that serum lipoprotein (a) [Lp (a)] concentration may take part in aggravation of diabetic nephropathy
While atherosclerosis is a major complication associated with diabetes mellitus(DM), various studies has been focused on elucidating the possible role of Lp(a) in this disease, when epidemiological studies have implicated high levels of plasma lipoprotein(a) with increased risk for atherosclerotic cardiovascular disease[8]
To evaluate the association of Lp(a) and hypertension(HTN) as a part of diabetic nephropathy aggravation, Nasri conducted a study on T2D patients[17], who were under treatments of oral hypoglycemic agents or insulin injections[17]
Summary
Implication for health policy/practice/research/medical education: Studies suggested that serum lipoprotein (a) [Lp (a)] concentration may take part in aggravation of diabetic nephropathy. It seems that serum Lp (a) can be considered as a promising predictive factor for the diagnosis of earlier diabetic nephropathy, prospective studies are needed to determine its role. While atherosclerosis is a major complication associated with diabetes mellitus(DM), various studies has been focused on elucidating the possible role of Lp(a) in this disease, when epidemiological studies have implicated high levels of plasma lipoprotein(a) with increased risk for atherosclerotic cardiovascular disease[8].
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