Abstract
Schematic illustration of the observational and genetic evidence that LDL-cholesterol (LDL-C) and lipoprotein(a) [Lp(a)] might be involved in the pathogenesis of aortic valve stenosis and/or aortic valve calcification. Recent trials with statins had no effect on the aortic valve outcomes. Questions concerning trials to be planned with Lp(a)-lowering drugs are listed. OxPL, oxidized phospholipids.
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