Abstract

Lipopolysaccharide binding protein (LBP) is an acute phase hepatic glycoprotein immediately involving in the process of immune response to endotoxin. Elevation of LBP appears to be an important marker associated with release of endotoxin and/or bacteriemia. In our study we investigated serum LBP levels as a prognostic marker for sepsis and Systemic Inflammatory Response Syndrome (SIRS). Also we assessed the correlation of LBP with procalcitonin (PCT), expression HLA-DR on monocytes and the production of TNF-α ex vivo by monocytes stimulated by lipopolysaccharide (markers of immunoparalysis).

Highlights

  • Intra-abdominal pressure (IAP) is an important parameter and prognostic indicator of the patient’s underlying physiologic status [1]

  • Several small studies have suggested that closed suction catheters offer benefits over open suction because disconnection from the ventilator circuit is not required [1], thereby maintaining ventilation, FIO2 and PEEP

  • On the bases of the experience of 96 self-practiced dilatational tracheostomies we critically report our experiences with two different kind of tracheostomy-sets

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Summary

Introduction

Intra-abdominal pressure (IAP) is an important parameter and prognostic indicator of the patient’s underlying physiologic status [1]. The aim of this study was to assess the respiratory effects of sufentanil and remifentanil in postsurgical critically ill patients during spontaneous ventilation since the drugs show pharmacokinetic and pharmacodynamic properties which make them attractive for intensive care use. Preliminary evidence suggests that hU-II levels during cardiac surgery are increased in patients with myocardial dysfunction [2] It is not known, if hU-II plasma concentrations are related to pulmonary capillary wedge pressure (PCWP) as an estimate of left ventricular filling pressure. AAF in cardiac surgery postoperative period has been implicated as a complication that leads to longer ICU and hospital stay and to augmented costs It has not been associated with increased mortality rates. We aimed to investigate the effects of use of preoperative and early postoperative standard and immunonutrient products on immune system and acute inflammatory response in the patients undergoing gastrointestinal malignancy surgery.

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