Abstract

Lipopeptide antibiotic production by Bacillus velezensis KLP2016

Highlights

  • The indiscriminate and excessive use of xenobiotics to control the plant diseases has disturbed the ecological balance of the soil leading to the development of resistant strains of pathogens, groundwater contamination and health risks to humans (Meena et al, 2014)

  • The crude lipopeptide of B. velezensis showed 45.0 ± 1.2% and 70.6 ± 2.4% growth inhibition of Aspergillus niger and Mucor sp., respectively by the Agar welldiffusion assay on Potato Dextrose Agar (PDA) plates

  • One of the isolates (LP-3; Figure 1a), which was Gram positive, rod shaped bacterium possessed highest antifungal activity was selected for extraction of LPs

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Summary

Introduction

The indiscriminate and excessive use of xenobiotics to control the plant diseases has disturbed the ecological balance of the soil leading to the development of resistant strains of pathogens, groundwater contamination and health risks to humans (Meena et al, 2014). Today one of the major challenges being faced by the biologists is the development of environmental friendly alternatives to the use of chemical pesticides to counter a variety of crop diseases (Ongena and Jacques, 2007; Meena and Kanwar, 2015). The increasing drug resistance in microorganisms has prompted a need to search potent alternative antimicrobial molecules like lipopeptides (LPs) with a new mode of action for use in agriculture, preservation of food and dairy products (Mandal et al, 2013).

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