Abstract
Although lipomatous tumors are the most common type of mesenchymal tumors in adults, they account for less than 10% of all soft tissue lesions in pediatric patients. In this descriptive study, we aim to present our series of pediatric lipomatous tumors consisting of lipoma, neural fibrolipoma, lipoblastoma, atypical lipomatous tumor, myxoid liposarcoma and pleomorphic liposarcoma, and to evaluate the clinicopathological characteristics of these tumors in reference to the literature. In this study, pediatric lipomatous tumor cases diagnosed between 2002 and 2018 were screened from pathological archives and retrospectively evaluated. A total of 50 cases were diagnosed with lipomatous tumor within the mentioned period. Of the total cases, 24 were female (48%) and 26 were male (52%), with age distribution ranging from 1 to 204 months. Histopathological examination revealed lipoma in 26 cases (52%), lipoblastoma in 19 (38%), atypical lipomatous tumor in 2 (4%), myxoid liposarcoma in 2 (4%), and pleomorphic liposarcoma in 1 case (2%). Although lipomatous tumors are the most common type of mesenchymal tumors; they rarely occur in children. Since there is a limited number of studies on pediatric lipomatous tumors in the literature, there is insufficient data on the prevalence and incidence of these tumors. These tumors may slowly enlarge to greater sizes, especially those localized in deep tissues, and may cause various clinical symptoms by compressing surrounding tissues. Local recurrences may occur, even after total excision, and require close monitoring.
Highlights
Lipomatous tumors including lipoma, lipoblastoma, hibernoma, atypical lipomatous tumor and liposarcoma play an important role in soft tissue pathology, as they are common in adults
Lipomatosis can be detected from 2 years of age, patients are usually diagnosed in adulthood
We aim to present our series of pediatric lipomatous tumors including lipoma, neural fibrolipoma, lipoblastoma, atypical lipomatous tumor, myxoid liposarcoma and pleomorphic liposarcoma, and evaluate the clinicopathological characteristics of these tumors in reference to the literature
Summary
Lipomatous tumors including lipoma, lipoblastoma, hibernoma, atypical lipomatous tumor and liposarcoma play an important role in soft tissue pathology, as they are common in adults. Lipomatosis can be detected from 2 years of age, patients are usually diagnosed in adulthood. Unlike other types of benign lipomatous tumors, 90% of patients with lipoblastoma are diagnosed under 3 years of age, and very few are adolescents or adults. Atypical malignant lipomatous tumors, which account for 40-45% of all liposarcomas, are rarely seen in children. Myxoid liposarcoma, accounting for 15-20% of liposarcomas and 5% of soft-tissue sarcomas, typically occurs in adulthood, and is the most common type of liposarcoma in children and adolescents [1,2,3,4,5,6]. Lipomatous tumors account for less than 10% of soft-tissue lesions within the first two decades of life [7]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
