Abstract

Lipodystrophy -- a clinical condition characterized by loss of subcutaneous fat -- has been recognized as a complication of juvenile dermatomyositis (JDMS). In addition, lipodystrophy is associated with hirsutism, acanthosis nigricans, insulin resistance, and hyperlipidemia. These investigators examined 20 patients with JDMS for clinical and metabolic abnormalities associated with lipodystrophy. The 20 patients were categorized and assigned to 3 groups: In group 1 were 4 patients with lipodystrophy. Group 2 contained …

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