Abstract
Essentially all aspects of eukaryotic cell physiology depend on their compartmentalization and on membrane flux between these compartments mediated by small GTPases and their regulators, as well as by specific membrane lipids (Behnia and Munro, 2005 ). Talks at the Minisymposium on “Membrane Traffic: Dynamic and Regulation” featured how Rab-and Arf-family GTPases, together with diverse phospholipids, most notably phosphoinositides (Balla, 2013 ), control key cell functions ranging from plasma membrane compartmentalization to organelle contacts, endosomal fission, cell motility, intracellular signaling, and cell cycle progression.
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