Lipid regulation by early administration of irradiated chitosan and glutathione in heat-stressed broilers

Abstract

This research was conducted to determine the effect of irradiated chitosan and glutathione on lipid regulation of broiler and its impact on free radical compounds. One hundred broiler starter phase as the objects of research. The study used a completely randomized design (CRD) with experimental protocols method, consisting of nine treatments and three replications. Each replication consist of five broilers, namely P0 = without giving chitosan and glutathione, PA1 = given 100 ppm chitosan from the age of 4-35 days, PA2 = 450 ppm chitosan from the age of 4-35 days, PA3 = 100 ppm chitosan + 150 ppm glutathione from the age of 4-35 days, PA4 = 100 ppm chitosan + 150 ppm glutathione from the age of 4-35 days, PB1 = 300 ppm chitosan from the age of 20-35 days, PB2 = 450 chitosan ppm since the age of 20-35 days, PB3 = 100 ppm chitosan + 150 ppm glutathione since the age of 20-35 days and PA4 = 100 ppm chitosan + 150 ppm glutathione since the age of 20-35 days. Parameters observed in this study, namely regulators and broiler lipid transport (Apo A1, Apo A2, Apo B, Apo C, HDL, LDL), plasma lipids (triglycerides, total cholesterol, NEFA), The results showed that the administration of irradiated chitosan and glutathione had a significant effect (P<0.05) on regulators and broiler lipid transport by fed 450 ppm of irradiated chitosan with 150 ppm of glutathione. Based on the research results, it can be concluded that the administration of irradiated chitosan accompanied by glutathione induction in broiler rations can affect lipid regulation and biochemical aspects and performance as a result of this regulation. Giving chitosan as much as 450 ppm with 150 ppm induced glutathione since the early age of the finisher phase (20 days) was able to regulate lipid biosynthesis optimally with the best final body weight.